Holland, P.W.H., L.Z. Holland, N.A. Williams and N.D. Holland (1992). An amphioxus homeobox gene: sequence conservation, and spatial expression during development and insights into vertebrate evolution. Development 116:653-661.

Holland, N.D. and L.Z. Holland (1993). Serotonin-containing cells in the nervous system and other tissues during ontogeny of a lancelet, Branchiostoma floridae. Acta Zool. (Stockholm) 74:195-204.

Holland, N.D. and L.Z. Holland (1993). Embryos and larvae of invertebrate deuterostomes. Chapt. 3 in Essential Development Biology: an Experimental Approach. (C. Stern and P.W.H. Holland, eds.) I.R.L. Press, Oxford, pp. 21-32.

Holland, N.D., L.Z. Holland, Y. Honma and T. Fujii (1993). Engrailed expression during developmen t of a lamprey, Lampetra japonica: a possible clue to homologies between agnathan and gnathostome muscles of the mandibular arch. Development, Growth, Differentiation 35:153-162.

Holland, P.W.H., J. Garcia-Fern\'e0ndez, L Z. Holland, N.A. Williams and N. D. Holland (1994). The molecular control of spatial patterning in amphioxus. J. Mar. Biol. Assoc. U.K. 74:49-60.

Holland, N.D., Z. Kozmik and L.Z. Holland (1995). An amphioxus Pax gene, AmphiPax -1, expressed in embryonic endoderm, but not in mesoderm: implications for the evolution of class I paired box genes. Molecular Marine Biol. and Biotechnol. 4:206-214.

Holland, L.Z., D.A. Pace, M.L. Blink, M. Kene and N.D. Holland (1995). Sequence and expression of amphioxus alkali myosin light chain ( AmphiMLC-alk) throughout development: implications for vertebrate myogenesis. Devel. Biol. 171:665-676.

Holland, P.W.H., B. Koschorz, L.Z. Holland and B.G. Herrmann (1995). Conservation of Brachyury (T) genes in amphioxus and vertebrates: developmental and evolutionary implications. Development 121:4283-4291.

Holland, L.Z., P.W.H. Holland and N.D. Holland (1996). Revealing homologies between body parts of distantly related animals by in situ hybridization to developmental genes: Amphioxus versus vertebrates. In: Molecular Approaches to Zoology and Evolution. J.D. Ferraris and S. Palumbe (eds.). J.Wiley, pp. 267-282.

Holland, L.Z. and N.D. Holland (1996). Expression of AmphiHox-1 and AmphiPax-1 in amphioxus embryos treated with retinoic acid: insights into evolution and patterning of the chordate nerve cord and pharynx. Development 122:1829-1238.

Holland, N.D., G. Panganiban, E.L. Henyey and L.Z. Holland (1996). Sequence and developmental expression of AmphiDII, an amphioxus Distal-less gene transcribed in the ectoderm, epidermis and nervous system: insights into evolution of craniate forebrain and neural crest. Development 122:2911-2920.

Holland, L.Z. (1996). Muscle development in amphioxus: morphology, biochemistry, and molecular biology. Israel J. Zool. 42:S235-S246.

Zhang, S.C., N.D. Holland and L.Z. Holland (1997). Topographic changes in nascent and early mesoderm in amphioxus embryos studied by dil labeling and by in situ hybridization for a Brachyury gene. Dev. Genes Evol. 206:532-535.

Holland, L.Z., N.A. Williams and N.D. Holland (1997). Sequence and embryonic expression of the amphioxus engrailed gene ( AmphiEn ): the metameric pattern of transcription resembles that of its segment-polarity homolog in Drosophila. Development 124:1723-1722.

Kusakabe, R., T. Kusakabe, N. Satoh, N.D. Holland and L.Z. Holland (1997). Differential gene expression and intracellular mRNA localization of amphioxus actin isoforms throughout development: Implications for conserved mechanisms of chordate development. Dev. Genes Evol. 207:203-215.

Holland, N.D., S.-C. Zhang, M. Clark, G. Panopoulou, H. Lehrach and L.Z. Holland (1997). Sequence and developmental expression of AmphiTob, an amphioxus homolog of vertebrate Tob in the PC3/BTG1/Tob family of tumor suppressor genes. Developmental Dynamics 210:11-18.

Holland, L.Z. and N.D. Holland (1998). Developmental gene expression in amphioxus: New insights into the evolutionary origin of vertebrate brain regions, neural crest, and rostrocaudal segmentation. Am. Zool. 38:647-656.

Holland, L.Z., T.V. Venkatesh, A. Gorlin, R. Bodmer and N.D. Holland (1998). Characterization and developmental expression of AmphiNk 2-2, and NK2 class homeobox gene from amphioxus (Phylum Chordata; subphylum Cephalochordata). Dev. Genes and Evol. 208:100-115.

Glardon, S., L.Z. Holland, W.J. Gehring and N.D. Holland (1998). Isolation and developmental expression of the amphioxus Pax-6 gene (AmphiPax-6): insights into eye and photoreceptor evolution. Development 125:2701-2710.

Panopoulou, G.D., M.D. Clark, L.Z. Holland, H. Lehrach and N.D. Holland (1998). AmphiBMP2/4, an amphioxus bone morphogenetic protein closely related to Drosophila decapentaplegic and vertebrate BMP2 and BMP4: insights into evolu tion of dorsoventral axis specification. Developmental Dynamics 213:130-139.

Schubert, M., N.D. Holland and L.Z. Holland (1998). Amphioxus AmphiDRAL encoding a LIM-domain protein: expression in the epidermis but not in the presumptive neuroectoderm. Mech. Dev. 76:203-205.

Kozmik, Z., N.D. Holland, A. Kalousova, J. Paces, M. Schubert and L.Z. Holland (1999). Characterization of an amphioxus paired box gene, AmphiPax2/5/8: developmental expression patterns in optic support cells, nephridium, thyroid-like structures and pharyngeal gill slits, but not in the midbrain-hindbrain boundary region. Development 126:1295-1304.

Venkatesh, T.V., N.D. Holland, L.Z. Holland, M.-T. Su and R. Bodmer (1999). Sequence and developmental expression of amphioxus AmphiNk2-1: insights into the evolutionary origin of the vertebrate thyroid gland and forebrain. Dev. Genes Evol. 209:254-259.

Holland, N.D. and L.Z. Holland (1999). Amphioxus and the utility of molecular genetic data for hypothesizing body part homologies between distantly related animals. Amer. Zool. 39:630-640.

Kusakabe, R., N. Satoh, L.Z. Holland and T. Kusakabe (1999). Genomic organization and evolution of actin genes in the amphioxus Branchiostoma belcheri and Branchiostoma floridae Gene 227:1-9.

Holland, L.Z., M. Schubert, Z. Kozmik and N.D. Holland (1999). AmphiPax3/7 , an amphioxus paired box gene: insights into chordate myogenesis, neurogenesis, and the possible evolutionary precursor of definitive vertebrate neural crest. Evol. Dev. 1:153-165.

Holland, L.Z. and N.D. Holland (1999). Chordate origins of the vertebrate central nervous system. Curr. Op. Neurobiol. 9:596-602.

Schubert, M., L.Z. Holland and N.D. Holland (2000) Characterization of two amphioxus Wnt genes (AmphiWnt4 and AmphiWnt7b) with early expression in the developing central nervous system. Dev. Dynamics 217:205-215.

Schubert, M., L.Z. Holland, G.D. Panopoulou, H. Lehrach and N.D. Holland (2000). Characterization of amphioxus AmphiWnt8: insights into the evolution of patterning of the embryonic dorsoventral axis. Evol. Dev. 2:85-92.

Holland, L.Z. (2000) Body-plan evolution in the Bilateria: early antero-posterior patterning and the deuterostome-protostome dichotomy. Curr. Op. Genetics Dev. 10:434-442.

Schubert, M., L.Z. Holland and N.D. Holland (2000). Characterization of an amphioxus Wnt gene, AmphiWnt11, with possible roles in myogenesis and tail outgrowth. Genesis 27:1-5.

Langlois, M.-C., J.-M. Vanacker, N.D. Holland, H. Escriva, C. Quev a, V. Laudet and L.Z. Holland (2000). Amphicoup-TF, a nuclear orphan receptor of the lancelet Branchiostoma floridae, is implicated in retinoic acid signalling pathways. Dev. Genes Evol. 210:471-482.

Holland, L.Z., N.D. Holland and M. Schubert (2000). Developmental expression of AmphiWnt1, an amphioxus gene in the Wnt1/wingless subfamily. Dev. Genes Evol. 210:522-524.

Schubert, M., L.Z. Holland, N.D. Holland and D.K. Jacobs (2000). A phylogenetic tree of the }{\i Wnt}{ genes based on all available full- length sequences, including five from the cephalochordate amphioxus. Molecular Biology and Evolution 17: 1896-1903.

Holland, L.Z., M. Schubert, N.D. Holland and T. Neuman (2000). Evolutionary conservation of the presumptive neural plate markers AmphiSox1/2/3 and AmphiNeurogenin in the invertebrate chordate amphioxus. Dev. Biol. 226:18-33.

Holland, L.Z., L. Abi Rached, R. Tamme, D. Kortschak, N. D. Holland, H. Inoko, T. Shiina, C. Burgtorf, and M. Lardelli (2001). Characterization and developmental expression of the amphioxus homolog of Notch ( AmphiNotch): Evolutionary conservation of multiple expression domains in amphioxus and vertebrates. Dev. Biol. 232: 493-507.

Kozmik, Z., L. Z. Holland, M. Schubert, T. C. Lacalli, J. Kreslova, C. Vlcek, and N. D. Holland (2001). Characterization of amphioxus amphivent, an evolutionarily conserved marker for chordate ventral mesoderm. Genesis 29: 172-179.

Holland, L.Z. and N.D. Holland (2001). Amphioxus and the evolutionary origin of the vertebrate neural cr est and midbrain/hindbrain boundary. In: Major Events in Early Vertebrate Evolution. P. Ahlberg, ed., Taylor and Francis Ltd. 2000. Pp. 15-32.

Holland, L. Z. (2001). Heads or Tails? Amphioxus and the Evolution of Anterior/posterior Patterning in Deuterostomes. Dev. Biol. In press.

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